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Nolvadex is a powerful antiestrogen that is used to prevent and treat breast cancer. Together with other medications, the drug can treat cancer that has spread to other parts of the organism, as well as multiple other types. Nolvadex is used by women during post-surgery and post-radiation period to eliminate the risk of cancer appearance.
Active Ingredient: tamoxifen
Availability: In Stock (36 packs)
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The use of hormone Nolvadex
Nolvadex belongs to the pharmacological group of anti-cancer hormonal remedies and hormone antagonists. Nolvadex has an antiestrogenic and anti-cancer pharmacological action. It is used in the treatment of women"s breast cancer, appearing at the time of menopause. Nolvadex is also used in the treatment of endometrial and kidney cancer and anovulatory infertility.
The active substance of Nolvadex is Tamoxifen. Actually, this substance acts as antagonist of estrogen, keeping to the receptors of this hormone. The essence of antiestrogenic action of this medicine is that the molecule of Tamoxifen, connected with the estrogen receptor, blocks the hormone. Due to the fact that many forms of breast cancer are sensitive to estrogen, the blocking action of Tamoxifen is successfully used in the treatment of this disease.
Composition and pharmaceutical form of Nolvadex
1 membrane-coated pill contains 10 or 20 mg of Tamoxifen (in the form of citrate); there are 10 pills in blister and 3 blisters in a box.
Pharmacological action: antiestrogenic and anti-cancer.
Rapidly absorbed. The maximal concentration in blood creates after 4-7 hours.
The equilibrium concentration (300 mg/mg) is achieved at a daily dose 40 mg for 4 weeks. The medicine is connected to albumin by 99 %. Tamoxifen is metabolized and excreted with the feces. The biological half-life of Tamoxifen is 7 days, X- desmethyltamoxifen (the main metabolite) - 14 days.
Indications for use of Nolvadex
Blood rushes, vaginal bleeding, endometrial hyperplasia, itching of vulva, dyspeptic disorders, dizziness, water retention in the body, hypercalcemia, thrombocytopenia, alopecia, uterine fibroid, leukopenia, thromboembolism.
Potentiates the effect of anticoagulants. In combination with cytotoxic remedies, the drug can cause thromboembolic complications.
Mode of application and dosage
To be taken (in the treatment of breast cancer- 20–40 mg a day at 1 or 2 times).
Storage conditions of Nolvadex
To be stored in the dark place at the temperature no higher than 30 °C. Keep away from children.
Storage life of Nolvadex
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